Instant Reprieve
Rapid Hybridization is a concise answer that trades one problematic creature for a tidy 3/3 body on the opponent side. As an Instant it fits into reactive blue shells that need spot removal without committing to a permanent answer. Use it to stop a lethal attacker, clear a blocker, or remove an engine piece while still leaving you tempo options on the following turn.
The Ravnica flavor here plays well with clues and city intrigue. The card name and the art imply sudden biological tinkering turned against a target. In practice this is efficient removal in limited and casual constructed play. It does not regenerate the target which makes it reliable against decks that rely on that keyword yet gives the opponent a tangible resource to weigh in future combat or blockers.
Card Details:
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Mana Cost – {U}
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Card Type – Instant
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Subtypes –
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Card Text / Rules Text (Printed) – Destroy target creature. It can’t be regenerated. That creature’s controller creates a 3/3 green Frog Lizard creature token.